Liv 52 Research and Case Studies

Liv 52 Research & Case Studies

Himalaya Health Care Ltd is completely research oriented company. Indeed R&D allows himalaya healthcare to produce safe, efficacious and consistent remedies using ayurvedic principles.

Himalaya R&D department is focused on product development, quality control and standardization. All the products are derived through rigorous research and produced in state-of-the art facilities. Each Himalaya product undergoes years of primary research before it reaches the market.

Recognition
In March 2001,Received Good Manufacturing Practices (GMP) Certificate, from Licensing Authority, Directorate of Indian Systems of Medicine, Bangalore. Himalaya is the first Ayurvedic facility to get GMP certification in the country.

Himalaya Healthcare Ltd is the only phytopharmaceutical company whose ayurvedic product, Liv.52, a hepato-protective formula, is registered as a 'pharmaceutical specialty' in Switzerland.

Switzerland.
Himalaya's R&D wing has been recognized as a Research Center by the Rajiv Gandhi University of Health Sciences, Karnataka, India.

Research Activities
Pharmacognosy
Establish bonafides of herbal materials through morphological and microscopic studies
Maintain herbarium of phyto-medical materials.
Formulation and Development
Pre-formulation studies to check the biochemical action of ingredients.
Trials to assess safety and efficacy of formulations.
Accelerated stability trials to check physical, chemical, microbiological and biological

1.	Liver disorders during pregnancy and their management During pregnancy, the human body undergoes several changes in the process of its adaptation to the growing fetus. Although these changes are physiological, there is potential for morbidity and mortality to both mother and fetus. Liver is the site of many important metabolic and synthetic functions of the body. Read More...
2.	Liv.52 DS tablets in acute viral hepatitis Viral hepatitis (A, B, C, D, E and G) is a global public health problem, which is responsible for a major chunk of morbidity and mortality. Viral hepatitis occurs endemically and sporadically throughout the world, depending on the endemicity of infection. Read More...
3.	Liv.52 in chronic active hepatitis and cirrhosis Amongst the wide spectrum of liver diseases prevalent all over the world, incidence of Infective Hepatitis, Chronic Active Hepatitis and Cirrhosis of the Liver comprises a very large group which is responsible for a high rate of mortality and morbidity amongst the population at large all over India Read More...
4	Liv.52 in hepatitis including precoma and coma The aim of the study was to evaluate the effects of the drug Liv.52 in the age group of 2-12 years on the course of infective hepatitis, including cases of precoma and coma, and also to find out the side effects of the drug if any. Read More...
5.	Liv.52 in infective hepatitis Acute infective hepatitis is a common infectious disease due to a virus which spreads by oral and faecal contamination. In this study there were 32 cases of infective hepatitis, moderate to severe, from an endemic malarial area. Read More...
6.	Live 52 and Toxamines of Pregnancy Pregnancy is a natural physiological process which, in a healthy and normally developed woman, should go on uneventfully without any degree of disturbance.Pregnancy involves a strain on all systems of the body as well as on the all important excretory functions,... Read More...
7.	Liv.52 in Mice Experimentally Infected with Semliki Forest Encephalitis Virus There are several reports in literature to show that plants may be effective sources of supply of antiviral agents. Kucera et al.¹, drew attention to antiviral activity of extract of lemon balm (Melissa officianlis) plant against at least four mammalian viruses tested in tissue culture models. Read More...
8.	Management of Infective Hepatitis The term Infective Hepatitis is confusing. Viral Hepatitis is the appropriate term. It includes Infective Hepatitis, Serum Hepatitis and Hepatitis caused by yellow fever. Read More...
9.	Role of Liv.52 in the treatment of infective hepatitis Infective Hepatitis is very common in Cachar District of Assam. Most patients when referred to the hospital are in fairly advanced stage with deep jaundice and deranged state of mind, etc. Read More...
10.	Infective hepatitis and Liv.52 drops Infective Hepatitis has become a problem for the physicians, the community and the Government in many parts of India. Read More...
11.	Liv.52 therapy in acute infective hepatitis Infective Hepatitis is a viral disease affecting mainly the hepatic parenchyma, producing changes typical of acute hepatitis, changes in biochemical parameters and histopathological changes in the liver. Read More...
12.	Role of Liv.52 in the treatment of infective hepatitis Various types of drugs are used in the treatment of Infective Hepatitis, e.g. antibiotics, vitamins, prednisolone and Liv.52. Read More...
13.	Study of Liv.52 therapy in infective hepatitis in children Infective hepatitis is one of the common hepatic disorders of infancy and childhood. It is endemic in our country and occasionally assumes epidemic proportion. Read More...
14.	Viral Hepatitis and Liv.52 Viral or infective hepatitis is quite a common condition characterised by a short incubation period. A 20-year-old male presented for treatment with a classic picture of Infective Hepatitis. Read More...
15.	Liv.52 in acute viral Hepatitis — Results of a double blind study A double blind trial with Liv.52 in acute viral hepatitis was carried out in the Department of Gastroenterology, Osmania General Hospital, Hyderabad. Read More...
16.	Effect of an indigenous preparation Liv.52 on Hepatitis B Antigen-Carriage The hepatitis B antigen (HBs Ag) is the surface antigen of the hepatitis B virus. HBs Ag can be demonstrated in patients’ sera by the simple immunological techniques of precipitation in gels. Read More...
17.	Preliminary Report on the Role of Liv.52–An Indigenous Drug in Serum B Hepatitis Cases Patney Patients with acute viral hepatitis have a severe course of illness, often characterised by anorexia, mild fever, hepatomegaly, splenomegaly, ascites and jaundice. Read More...
18.	Acute Hepatic Failure with Special Reference to Liv.52 Therapy Acute hepatic failure is a clinical syndrome characterised by severe impairment of liver function and mental changes of various grades. Read More...
19.	Liv.52 therapy in viral hepatitis Rowland (1972) in his study on epidemiology of infectious hepatitis has said that persons of all races and all ages are susceptible to infectious hepatitis. Read More...
20.	A Clinical study of infective Hepatitis treated with Liv.52 In children, liver disorders such as infective hepatitis or cirrhosis of the liver are quite common. Of these, the incidence of infective hepatitis is relatively high. Read More...
21.	Observations on the treatment of infective Hepatitis with an indigenous drug Liv.52 Infective hepatitis accounts for nearly 90% of all jaundice cases in our country. The mode of infection is oro-faecal. Read More...
22.	Clinical Trial of Liv.52 Drops in Infective Hepatitis Hepatic disorders in infancy and childhood continue to pose problems in their management. Viral hepatitis in our country is frequently of prolonged duration with a predisposition to complications... Read More...
23.	Viral Hepatitis in Children During the past few decades, particularly since World War II, viral hepatitis has become an increasingly important public health problem throughout the world. Read More...
24.	Efficacy of an Indigenous Compound Preparation Liv.52 in Acute Viral Hepatitis Viral hepatitis is an endemic disease in our country assuming epidemic proportions occasionally. Though majority of patients recover completely with no residual liver damage, ... Read More...
25.	A Study of chronic Hepatitis in northern India Chronic hepatitis is defined as persistent or progressive liver disease characterised by clinical, biochemical and morphological evidences of hepatic dysfunction of more Read More...
26.	Viral Hepatitis in Children Viral hepatitis is one of the commonest causes of jaundice in children and is one of the diseases still unconquered even in the West. Read More...
27.	Studies on Liv.52 in hepatic disorders In Part I of their Paper the Authors reported on 58 Cases of Viral Hepatitis. Of these 32 cases were treated with Liv.52 and supportive therapy while 26 cases served as controls and received only ... Read More...
28.	Liv.52 in infective Hepatitis Infective hepatitis is one of the important causes of jaundice in children in this country. It is endemic in the city of Bhopal. Read More...
29.	Acute Infectious Hepatitis with Fulminant Hepatic Failure Acute infectious hepatitis is by far the most common form of hepatitis. It occurs sporadically and in epidemics. Read More...
30.	Trial of Liv.52 in Infectious Hepatitis in Children in Goa Infectious hepatitis produces an acute inflammation of the liver which, though mild and self limiting in many cases, often runs an acute fulminating and fatal course or results in severe,... Read More...
31.	Studies with Liv.52 in Infective Hepatitis Liv.52, an indigenous product has been widely used clinically in various hepatic disorders for the last eight years. Read More...
32.	Liv.52 Therapy in Infective Hepatiti Infective hepatitis though not one of the commonest diseases affecting children, certainly does not belong to the group of uncommon diseases. Read More...
33.	Liv.52 in Viral Hepatitis with Special Reference to its use in Precoma and Coma Viral Hepatitis is a systemic viral disease with predominant involvement of the liver. It is a disease of varying severity ranging from mild anicteric hepatitis to acute fulminating hepatitis leading to ... Read More...
34.	Role of Liv.52 and Steroids in the Management of Viral Hepatitis in Children Viral hepatitis is one of the diseases which remains unconquered even in the Western countries. The incidence of the disease in advanced countries like U.S.A. is 33 per 1,00,000 population30. Read More...
35.	Studies on Liv.52 in hepatic disorders Liver diseases continue to be one of the major causes of morbidity and mortality in children. The treatment of most of the diseases remains non-specific, Read More...
36.	Observations on the therapy of acute infectious hepatitis with Liv.52 The liver holds a place of singular importance in maintaining human health. It controls numerous metabolic processes via the metabolic pool. Read More...
37.	Studies on 222 cases of Acute Infective Hepatitis During an Epidemic Infective hepatitis is a well recognised communicable disease caused by a virus. It produces clinical, symptomatic and general effects. Read More...
38.	Liv.52 trial in Infective Hepatitis Infective hepatitis which occurs in all parts of the World is caused by a virus which was named Virus IH by Neefee. Read More...
39	Liv.52 in the Treatment of Acute Infective Hepatitis Many drugs have been tried for the therapy of acute infective hepatitis. Chemotherapeutic agents and antibiotics have been demonstrated to be of little use. Read More...
40.	Clinico-biochemical study of Infective Hepatitis with Special Reference to Liv.52 Therapy Infective hepatitis is an acute communicable disease caused by a virus characterised clinically by symptoms ranging from slight malaise to severe hepatitis and jaundice,... Read More...
41.	Therapeutic Effects of Liv.52 in Post-Necrotic Hepatitis Infectious hepatitis is encountered in paediatric practice either during an epidemic or as sporadic cases. Clinically it may present in mild, moderate or severe forms. Read More...
42.	Therapy of Infectious Hepatitis and Other Liver Disorders Hepatic disorders in infancy and childhood continue to pose problems in regard to their management. Even though the aetiological factors are many and some of them ill-understood Read More...
43.	Therapy of Infectious Hepatitis and Other Liver Disorders Viral hepatitis as observed in our country is frequently of prolonged duration with a predisposition to complications like post-hepatitis cirrhosis, chronic cholestasis, ... Read More...
44.	Liv.52 Therapy in Viral Hepatitis Viral hepatitis as observed in our country is frequently of prolonged duration with a predisposition to complications like post-hepatitis cirrhosis, chronic cholestasis, Read More...
45.	Chronic Active Hepatitis A clinical syndrome of chronic hepatocellular dysfunction has been recognised recently by the term ‘Chronic Active Hepatitis’. Read More...
46.	Infections Hepatitis - Study of 100 Cases The well-recognised credo of students of human illness introduced by the founders of present day medicine is that a disease process can only be fully understood and interpreted Read More...
47.	Some Observations on Liv.52 in the Treatment of Infective Hepatitis and Cirrhosis of Liver Seven cases of infective hepatitis and three cases of cirrhosis of the liver from the Hospital for Children, Patna Medical College Hospital, were included in his study. Read More...
48.	Liv.52 Studies in Acute Hepatitis Of 250 cases of acute hepatitis studied and followed for 1 year, half were given Liv.52 and the other half either steroid therapy or placebo. Read More...
49	Infective Hepatitis — Survey and Study of 110 cases This is a study of 110 cases of infective hepatitis observed by us at the Hangal Primary Health Centre between August and October 1969. Read More...
50.	Treatment of viral hepatitis by an indigenous drug – Liv.52 Since World War II the diagnosis of infectious hepatitis in adults has been made from various parts of the globe with increasing frequency. The course of the disease varies in duration and severity. Read More...
51.	Liv.52 in Infective Hepatitis* Infective hepatitis is the main cause of jaundice in our country. It is endemic in the city of Hyderabad, as cases occur throughout the year. The majority of them take treatment elsewhere, Read More...
52.	Role of Various Types of Treatment in Infectious Hepatitis Infectious Hepatitis is a systemic illness with world-wide distribution. It is caused by a virus IH (A) of which three serologically different types have been isolated. Read More...
53	Studies with Liv.52 therapy in Infective Hepatitis Liv.52, an indigenous product has been widely used clinically in various hepatic disorders for the last eight years. The drug has been tried in cases of diffuse hepatic fibrosis and portal hypertension (Mathur, 1957). Read More...
54.	Preliminary Observation on the Role of Liv.52 in Infective Hepatitis with Persistent Jaundice Viral hepatitis poses a great problem in our country with a high degree of morbidity. Frequently it predisposes to more serious complications like post-hepatic cirrhosis, Read More...
55.	Liv.52 DS Tablets The present study was planned to evaluate Liv.52 DS tablet as a hepatoprotective agent in prophylaxis with statin therapy. Read More...
56.	Role of Liv.52 – A Herbal Formulation on 14C-Ethanol Metabolism and 14C-Acetaldehyde Accumulation in Rat Liver Ethanol consumption is a major cause of liver disease. Ethanol and its metabolites have been shown to be directly injurious to the liver1. Read More...
57.	Hepatoprotective Effects of Liv.52 on Ethanol-induced Liver Damage in Rats The mechanism of protective effects of Liv.52, a multiherbal hepatoprotective drug, on ethanol induced hepatic damage has been investigated. Read More...
58.	Effect of the Hepatoprotective Drug Liv. 52 on Liver Damage The action of hepatoprotective drugs is a subject of discussion. Despite the equivocal character of hepatoprotective drugs used, the effect is partly due to the placebo effect. Read More...
59.	Effect of the Hepatoprotective Drug Liv. 52 on Liver Damage A study was conducted on Wistar male rats to assess the effect of chronic alcohol administration on blood ethanol and acetaldehyde levels and their modification by Liv.52, an Ayurvedic formulation. Read More...
60.	Protective Effect of Liv.52 on Alcohol-Induced Fetotoxicity The adverse effects of maternal alcohol consumption on the development of the fetus are well known. Read More...
61.	Alcoholic Liver Disease – The Possibility of Ayurvedic Therapy There is a general revival of interest in the alternative systems of medicine partly because of the inadequacies of the modern westernised systems of medicine and their hazards including the ... Read More...
62.	Alcohol Hangover and Liv.52 Ethanol and acetaldehyde levels in blood and urine have been evaluated in 9 volunteers following administration of Liv.52 and placebo on the evening of the study and on the following morning. Read More...
63.	Effect of Liv52, A Herbal Preparation, on Absorption and Metabolism of Ethanol in Humans Chronic alcohol consumption is a prime cause of liver disease.1,2 Present evidence indicates that acetaldehyde, the intermediate metabolite of ethanol, Read More...
64.	Dose Response of Ethanol after Chronic Administration of Alcohol and Effect of Liv.52 on Blood, Chronic alcohol consumption in humans induces phase I metabolism of ethanol and decreases acetaldehyde clearance. Liv.52 treatment for 15 days in chronic alcohol users reversed these changes1. Read More...
65.	Blood, urine ethanol and acetaldehyde levels from six different alcoholic beverages Blood/urine ethanol and acetaldehyde levels were estimated after fixed dose of 43 gms of ethanol in the form of Whisky, Rum, Vodka, Gin, wine and Beer in six moderate alcohol users.Read More...
66.	Addiction and Industry Alcoholism and Drug Dependence are on the increase in industry. A survey of a number of larger industries in Bombay showed that the better paid the industrial workers, Read More...