Sanskrit / Indian Name : Mandur bhasma
English Name                : Ferric Oxide Calx

Mandur bhasma an ayurvedic preparation of iron is used in traditional medicine against hepatitis. In the present study the hepatoprotective property of this drug was tested in albino rats during CCl4 induced hepatic injury. The effect of mandur bhasma on the activities of the lipolytic enzymes of rat liver, kidney and adipose tissue were studied during hepatitis induced by CCI4. The activities of acid lipase, alkaline lipase, lipoprotein lipase and hormone sensitive lipase exhibited significant alterations during CCl4 induced hepatic injury, indicating a role for these enzymes in the mobilization of fat from adipose tissue and accumulation of fat in liver and kidney. Simultaneous treatment with mandur bhasma prevented the paraffin mediated and CCl4 mediated changes in the enzyme activities. These results suggest the hepatoprotective role of mandur bhasma during CCl4 induced hepatic injury.

Mandur bhasma found most effective in liver disorders. Corrects anaemia, jaundice, piles, oedema associated with liver disorders. Indicated in general debility, sexual debility, enlargement of spleen. Medicine of choice for growing children & pregnant women. Preferred as an haematinic. It is prepared by purifying and calcinating iron rust. Mandura is specially useful in anemia, amenorrhoea, dysmenorrhea, menorrhagia, chlorosis, hepatic and splenic disorders. It is also used in diarrhea, chronic bowel complaints, dyspepsia, intestinal worms, nervous diseases, neuralgia of the 5th nerve due to debility, kidney diseases, albuminuria, etc. It is a powerful hematinic and tonic and is valuable in the treatment of hemolytic jaundice and microcytic anemia.